STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7387Unfolded protein binding; heat shock protein binding. It is involved in the biological process described with: regulation of apoptotic process; protein folding; mitochondrion organization. (449 aa)    
Predicted Functional Partners:
CG12684
IP21517p.
   
  
 0.927
CG13690
Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
    
 
 0.923
CG4593
CG4593-PA.
      
 0.913
Hsc70-5
Heat shock 70 kDa protein cognate 5.
  
 
 0.873
CG6980
GH10293p.
   
 
 0.839
CG14717
CG14717 protein; Carboxylic ester hydrolase activity.
   
 
 0.821
CG11379
EG:BACR42I17.4 protein.
   
  
 0.725
Roe1
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
  
 
 0.721
CG15336
Uncharacterized protein; Sequence-specific DNA binding.
    
 
 0.670
Torsin
Torsin-like protein; Torsin (Torsin) encodes an AAA-ATPase that is implicated in the export of large ribonuclear protein particles through the nuclear membrane. It regulates dopamine levels; Belongs to the ClpA/ClpB family. Torsin subfamily.
      
 0.670
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.