STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNaseX25Endoribonuclease activity; RNA binding; ribonuclease T2 activity; ribonuclease activity. It is involved in the biological process described with: RNA catabolic process; multicellular organism reproduction; Belongs to the RNase T2 family. (325 aa)    
Predicted Functional Partners:
CG2818
LD22655p; Glycerophosphocholine phosphodiesterase activity; starch binding. It is involved in the biological process described with: glycerophospholipid catabolic process.
 
 
    0.758
CG11664
CG11664 encodes a protein with homology to serine-type endopeptidases, but is not predicted to have catalytic activity due to mutations in its active site. It is produced by the male accessory glands.
   
  
 0.671
CG17570
Uncharacterized protein.
      
 0.652
Cyp316a1
Probable cytochrome P450 316a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
   
  
 0.630
pst
Pastrel, isoform F; Pastrel (pst) encodes a protein involved in long-term memory and protein secretion.
      
 0.608
ubl
Ubiquitin-like protein 5; Protein tag. It is involved in the biological process described with: mRNA splicing, via spliceosome; cellular protein modification process.
   
  
 0.603
Appl
Amyloid-beta-like protein; During development, plays a role in the regulation of the neddylation pathway. Appl and APP-BP1 interact antagonistically during development; Belongs to the APP family.
      
 0.601
Glg1
Golgi complex-localized glycoprotein 1, isoform B; Fibroblast growth factor binding.
      
 0.573
chic
Profilin; Chickadee (chic) encodes an actin monomer binding protein that provides the major cellular pool of readily polymerizing ATP-actin monomers. It is involved in oogenesis, spermatogenesis, cell division, bristle formation, cellular morphogenesis, axon growth, filopodia formation, dorsal closure, wound healing and stem cell maintenance.
   
  
 0.530
Cyp4d8
Cytochrome P450 4d8; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
   
  
 0.523
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.