STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG8111Transmembrane protein 43 homolog; It is involved in the biological process described with: nuclear membrane organization. (376 aa)    
Predicted Functional Partners:
CG4972
Nicalin; It is involved in the biological process described with: regulation of signal transduction; Belongs to the nicastrin family.
      
 0.610
CG6962
LD28817p; Sphingomyelin phosphodiesterase D activity. It is involved in the biological process described with: ceramide biosynthetic process; glycerophospholipid catabolic process; sphingomyelin catabolic process.
      
 0.588
Hacd2
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
  
 0.528
rempA
Reduced mechanoreceptor potential A (rempA) encodes the IFT140 subunit of the IFT-A subcomplex. As such, it is a component of the conserved intraflagellar transport (IFT) mechanism and is needed to extend cilia above the cell surface.
   
  
 0.507
CG8461
LD29276p; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cleavage involved in rRNA processing.
      
 0.439
Eig71Ee
Ecdysone-induced gene 71Ee (Eig71Ee) encodes a protein of unknown function. It is expressed in larvae in both salivary glue and the hemolymph clot, where it is a substrate of the product of Tg.
    
 
 0.436
CG13216
RE71337p.
    
 
 0.436
Hers
Histone gene-specific epigenetic repressor in late S phase, isoform A; Transcription regulatory region sequence-specific DNA binding; chromatin binding. It is involved in the biological process described with: chromatin silencing; chromatin remodeling.
      
 0.436
Kr-h2
Krueppel homolog 2; Member of the dosage-dependent hierarchy effective upon white gene expression; Belongs to the PER33/POM33 family.
      
 0.435
nuf
Nuclear fallout, isoform J; Nuclear fallout (nuf) encodes a cytoplasmic, coiled-coil protein that acts as an adaptor between the product of Rab11 and motor proteins in the recycling endosome pathway. It is required for early embryo cellularization, and for subsequent Rab11-dependent processes.
      
 0.426
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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