Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG7506Transmembrane protein 70 homolog, mitochondrial; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. (236 aa)    
Predicted Functional Partners:
ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Involved in the innate immune response. Promotes the production of antibacterial peptides; Belongs to the ECSIT family.
   
 
 0.971
CG4627
IP07454p.
   
  
 0.942
CG4042
FI07223p.
   
  
 0.922
CG13392
UT01133p; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly.
   
  
 0.917
140up
RPII140-upstream gene protein; Essential for viability.
   
  
 0.917
ND-15
NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform A; It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
    
 
 0.893
l(2)37Bb
Lethal (2) 37Bb; Oxidoreductase activity. It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly; oxidation-reduction process.
   
  
 0.860
sicily
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages; Belongs to the NDUFAF6 family.
   
  
 0.841
Egm
LP02372p; Enigma (Egm) encodes a mitochondrial oxidoreductase involved in oxidative stress response and lipid homeostasis.
   
  
 0.837
l(2)k14505
Lethal (2) k14505, isoform A; It is involved in the biological process described with: proton-transporting ATP synthase complex assembly.
   
  
 0.832
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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