Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG14820RE62864p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. (416 aa)    
Predicted Functional Partners:
CG15253
Zinc ion binding; metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
   
  
 0.810
CG7025
Peptidase_M14 domain-containing protein; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
  
   
0.769
CG18557
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
    
 
 0.592
Lectin-galC1
Galactose-specific C-type lectin (Lectin-galC1) encodes a galactose binding protein involved in the induction of bacterial agglutination and cell-cell adhesion.
      
 0.590
CG3106
GH10201p; Transferase activity, transferring acyl groups other than amino-acyl groups.
   
    0.571
kappaTry
KappaTry; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
   
 
 0.556
Ser6
Serine protease 6; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
 
 0.505
CG14200
Uncharacterized protein, isoform A.
      
 0.474
MtnD
Metallothionein-4; Metallothionein D (MtnD) encodes a member of the Metallothionein family whose transcription is strongly inducible by copper and cadmium ions. Its induction depends on the transcription factor encoded by MTF-1; Belongs to the metallothionein superfamily. Type 5 family.
      
 0.467
mt:ATPase8
ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]
      
 0.442
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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