| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASK | GluRIA | FBpp0303394 | FBpp0076691 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | 0.829 |
| CASK | GluRIIA | FBpp0303394 | FBpp0078739 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | 0.432 |
| CASK | GluRIIE | FBpp0303394 | FBpp0110134 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. | 0.817 |
| CASK | Nmdar1 | FBpp0303394 | FBpp0078410 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation. | 0.888 |
| CASK | Nmdar2 | FBpp0303394 | FBpp0070276 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | NMDA receptor 2, isoform C; Ligand-gated ion channel activity; signaling receptor activity; NMDA glutamate receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; glutamate receptor activity. | 0.872 |
| GluRIA | CASK | FBpp0076691 | FBpp0303394 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | 0.829 |
| GluRIA | GluRIIA | FBpp0076691 | FBpp0078739 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | 0.775 |
| GluRIA | GluRIIB | FBpp0076691 | FBpp0088541 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | 0.782 |
| GluRIA | GluRIIC | FBpp0076691 | FBpp0307912 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission. | 0.774 |
| GluRIA | GluRIIE | FBpp0076691 | FBpp0110134 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. | 0.775 |
| GluRIA | Neto | FBpp0076691 | FBpp0308760 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Neuropilin and tolloid-like (Neto) encodes a transmembrane protein with no catalytic activities. It associates with several inotropic glutamate receptors (iGluRs) and modulates their sub-cellular distribution and function. At the neuromuscular junction, it enables iGluR clustering at the onset of synaptogenesis, and triggers postsynaptic differentiation. | 0.783 |
| GluRIA | Nmdar1 | FBpp0076691 | FBpp0078410 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation. | 0.838 |
| GluRIA | Nmdar2 | FBpp0076691 | FBpp0070276 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | NMDA receptor 2, isoform C; Ligand-gated ion channel activity; signaling receptor activity; NMDA glutamate receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential; glutamate receptor activity. | 0.803 |
| GluRIA | PICK1 | FBpp0076691 | FBpp0309442 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Membrane curvature sensor activity; phospholipid binding; protein kinase C binding; protein domain specific binding. | 0.778 |
| GluRIA | stg1 | FBpp0076691 | FBpp0076940 | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | Stargazin-like protein (stg1) encodes a channel regulator that modulates both AMPA receptor activity and glutamatergic synaptic transmission. | 0.892 |
| GluRIIA | CASK | FBpp0078739 | FBpp0303394 | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | 0.432 |
| GluRIIA | GluRIA | FBpp0078739 | FBpp0076691 | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | Glutamate receptor 1; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. | 0.775 |
| GluRIIA | GluRIIB | FBpp0078739 | FBpp0088541 | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | 0.948 |
| GluRIIA | GluRIIC | FBpp0078739 | FBpp0307912 | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission. | 0.835 |
| GluRIIA | GluRIIE | FBpp0078739 | FBpp0110134 | Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. | Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. | 0.896 |