Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cpr65AzCuticular protein 65Az; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development. (239 aa)    
Predicted Functional Partners:
Ccp84Ae
Cuticle protein; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.912
Cpr73D
Cuticular protein 73D, isoform B; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.861
Cpr76Bd
Cuticular protein 76Bd (Cpr76Bd) encodes a cuticle component involved in adult fly melanization.
   
  
 0.826
Muc91C
Mucin 91C, isoform A; Extracellular matrix structural constituent.
    
 
 0.608
TwdlD
RE49895p; TweedleD (TwdlD) encodes a chitin-binding protein that is a member of the Tweedle family of cuticle proteins.
      
 0.590
TwdlS
RT12701p1; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: body morphogenesis; chitin-based cuticle development.
   
  
 0.534
dyl
Dusky-like, isoform A; Dusky-like (dyl) encodes a plasma membrane protein involved in actin filament organization. It is involved in apical constriction, cell-matrix adhesion and hair morphogenesis.
      
 0.469
Acp1
Adult cuticle protein 1; Component of the cuticle of the adult fruit fly. Could be involved in thickening of the hard adult cuticle.
      
 0.449
resilin
Pro-resilin; Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage.
   
 
 0.449
retinin
Retinin; Structural constituent of eye lens.
      
 0.423
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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