STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7386FI21277p1; DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated. (662 aa)    
Predicted Functional Partners:
CG17568
IP01252p; Zinc ion binding; nucleic acid binding; transcription corepressor activity. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II.
  
 
0.690
CG8159
RT10616p; Zinc ion binding; DNA-binding transcription factor activity; DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
  
 
0.682
CG10321
Uncharacterized protein, isoform B; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; zinc ion binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II.
      
 0.660
CG17802
RE19693p; DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
  
 
0.617
CG2202
RE22038p; Transcription regulatory region sequence-specific DNA binding; DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
  
 
0.612
CG31457
LD10183p; Protein phosphatase 1 binding; zinc ion binding.
      
 0.607
grau
Grauzone (grau) encodes a transcription factor with the Cdc20 activator of the Anaphase Promoting Complex (APC) encoded by cort as key target. Absence of grau function results in the cort phenotype of female sterility, meiosis II arrest, and egg activation defects.
  
 
 
0.602
CG13506
FI23916p1; Axon guidance receptor activity. It is involved in the biological process described with: synapse organization; homophilic cell adhesion via plasma membrane adhesion molecules.
      
 0.602
ouib
Transcription factor Ouib; Transcription factor required for ecdysteroid production in the prothoracic gland by activating transcription of the ecdysteroid biosynthesis gene spok. Binds to the 5'-AGCTTTATTATTTAG-3' DNA sequence in the spok enhancer region.
 
  
0.597
ranshi
Ranshi (ranshi) encodes a protein involved in oocyte differentiation.
  
 
0.569
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.