Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CG6592Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (438 aa)    
Predicted Functional Partners:
CG42592
Uncharacterized protein.
      
 0.743
CG5853
FI22810p1; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.655
PPO3
Phenoloxidase 3; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone (By similarity).
      
 0.600
CG10081
RE61138p; It is involved in the biological process described with: proteolysis.
   
  
 0.542
CG1503
CG1503-PA; Cysteine-type peptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.512
CG30288
RT07670p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.506
CG8539
FI17864p1; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.
   
 
 0.488
CG8560
GH20109p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
    
 
 0.477
CG32483
Uncharacterized protein; Serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase S10 family.
      
 0.473
CG3739
Uncharacterized protein; Serine-type peptidase activity; dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.473
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (40%) [HD]