STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10467Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (364 aa)    
Predicted Functional Partners:
Gale
UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP- Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconvers [...]
 
  
 0.961
Gal
Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family.
  
 
 0.918
Ect3
Beta-galactosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
  
 
 0.917
CG7997
Alpha-galactosidase activity. It is involved in the biological process described with: glycosylceramide catabolic process; glycoside catabolic process; oligosaccharide metabolic process.
   
 
 0.907
CG6650
LD24362p; ADP-specific glucokinase activity. It is involved in the biological process described with: carbohydrate metabolic process.
     
  0.900
G6P
Glucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process.
     
  0.900
Galk
Galactokinase, isoform A; Galactokinase (Galk) encodes a protein involved in galactose metabolism that regulates calcineurin-induced cardiac enlargement.
  
 
 0.762
Akr1B
AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process.
   
 
 0.678
CG10863
BcDNA.GH10614; alditol:NADP+ 1-oxidoreductase activity; indanol dehydrogenase activity; oxidoreductase activity; alcohol dehydrogenase (NADP+) activity. It is involved in the biological process described with: oxidation-reduction process.
   
 
 0.675
Hex-C
Phosphotransferase; Hexokinase C (Hex-C) encodes a hexokinase involved in glucose homeostasis.
   
 
 0.672
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.