Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG8031 | Egfr | FBpp0082187 | FBpp0071571 | LP04475p; It is involved in the biological process described with: regulation of microtubule-based process. | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | 0.721 |
| CG8031 | vn | FBpp0082187 | FBpp0076790 | LP04475p; It is involved in the biological process described with: regulation of microtubule-based process. | Vein (vn) encodes a secreted neuregulin-like EGFR ligand. It has weaker intrinsic activity, and a lower receptor affinity, than the TGFalpha-like ligand encoded by spi. It has roles in growth and patterning of tissues including muscle, midgut, ovary, trachea, glia, eye, leg, and wing. | 0.706 |
| Csk | Egfr | FBpp0289007 | FBpp0071571 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | 0.874 |
| Csk | Ras85D | FBpp0289007 | FBpp0081600 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.772 |
| Csk | Shc | FBpp0289007 | FBpp0076186 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | SHC-adaptor protein (Shc) encodes a protein involved in receptor tyrosine kinase signalling. It regulates anti-parasitoid immune response and tracheal development. | 0.965 |
| Csk | Src64B | FBpp0289007 | FBpp0310444 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.991 |
| Csk | vn | FBpp0289007 | FBpp0076790 | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | Vein (vn) encodes a secreted neuregulin-like EGFR ligand. It has weaker intrinsic activity, and a lower receptor affinity, than the TGFalpha-like ligand encoded by spi. It has roles in growth and patterning of tissues including muscle, midgut, ovary, trachea, glia, eye, leg, and wing. | 0.729 |
| Egfr | CG8031 | FBpp0071571 | FBpp0082187 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | LP04475p; It is involved in the biological process described with: regulation of microtubule-based process. | 0.721 |
| Egfr | Csk | FBpp0071571 | FBpp0289007 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | C-terminal Src kinase (Csk) encodes a cytoplasmic tyrosine kinase that acts as a tumor suppressor through Src pathway inibition as well as a mediator of the activity of the product of Egfr. | 0.874 |
| Egfr | Pi3K21B | FBpp0071571 | FBpp0303635 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Pi3K21B, isoform B; Pi3K21B (Pi3K21B) encodes an adaptor protein (p60) that binds the product of Pi3K92E to form the functional cllass IA phosphoinositide 3-kinase. This heterodimeric kinase is involved in phosphatidylinositol phosphorylation and regulates cell size and proliferation. | 0.886 |
| Egfr | Ras85D | FBpp0071571 | FBpp0081600 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.993 |
| Egfr | Shc | FBpp0071571 | FBpp0076186 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | SHC-adaptor protein (Shc) encodes a protein involved in receptor tyrosine kinase signalling. It regulates anti-parasitoid immune response and tracheal development. | 0.998 |
| Egfr | Src64B | FBpp0071571 | FBpp0310444 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Tyrosine-protein kinase Src64B; Src oncogene at 64B (Src64B) encodes a Src family nonreceptor tyrosine kinase. It has many biological roles, including ring canal morphogenesis in oogenesis and the male germline, microfilament ring constriction during cellularization, and modulation of growth and apoptosis. Some of its roles overlap with those of the product of Src42A. | 0.855 |
| Egfr | dos | FBpp0071571 | FBpp0072803 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Protein daughter of sevenless; Essential component for signaling from various receptor tyrosine kinases such as Sevenless, TORSO and DER. Required for photoreceptor cell and wing development. | 0.966 |
| Egfr | elgi | FBpp0071571 | FBpp0075265 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Early girl (elgi) encodes a myosin binding protein involved in the regulation of meiosis and Fat signaling pathway. | 0.943 |
| Egfr | spi | FBpp0071571 | FBpp0080809 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Protein spitz; Ligand for the EGF receptor (Gurken). Involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development. It is required for photoreceptor determination. | 0.999 |
| Egfr | vn | FBpp0071571 | FBpp0076790 | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | Vein (vn) encodes a secreted neuregulin-like EGFR ligand. It has weaker intrinsic activity, and a lower receptor affinity, than the TGFalpha-like ligand encoded by spi. It has roles in growth and patterning of tissues including muscle, midgut, ovary, trachea, glia, eye, leg, and wing. | 0.994 |
| Pi3K21B | Egfr | FBpp0303635 | FBpp0071571 | Pi3K21B, isoform B; Pi3K21B (Pi3K21B) encodes an adaptor protein (p60) that binds the product of Pi3K92E to form the functional cllass IA phosphoinositide 3-kinase. This heterodimeric kinase is involved in phosphatidylinositol phosphorylation and regulates cell size and proliferation. | Epidermal growth factor receptor; Binds to four ligands: Spitz, Gurken, Vein and Argos, which is an antagonist. Transduces the signal through the ras-raf-MAPK pathway. Involved in a myriad of developmental decisions. Critical for the proliferation of imaginal tissues, and for the determination of both the antero-posterior and dorso-ventral polarities of the oocyte. In the embryo, plays a role in the establishment of ventral cell fates, maintenance of amnioserosa and ventral neuroectodermal cells, germ band retraction, cell fate specification in the central nervous system and production [...] | 0.886 |
| Pi3K21B | Ras85D | FBpp0303635 | FBpp0081600 | Pi3K21B, isoform B; Pi3K21B (Pi3K21B) encodes an adaptor protein (p60) that binds the product of Pi3K92E to form the functional cllass IA phosphoinositide 3-kinase. This heterodimeric kinase is involved in phosphatidylinositol phosphorylation and regulates cell size and proliferation. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.924 |
| Pi3K21B | Shc | FBpp0303635 | FBpp0076186 | Pi3K21B, isoform B; Pi3K21B (Pi3K21B) encodes an adaptor protein (p60) that binds the product of Pi3K92E to form the functional cllass IA phosphoinositide 3-kinase. This heterodimeric kinase is involved in phosphatidylinositol phosphorylation and regulates cell size and proliferation. | SHC-adaptor protein (Shc) encodes a protein involved in receptor tyrosine kinase signalling. It regulates anti-parasitoid immune response and tracheal development. | 0.792 |
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