STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slgAProline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. (681 aa)    
Predicted Functional Partners:
CG6661
GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process.
  
 0.991
P5CDh1
delta-1-Pyrroline-5-carboxylate dehydrogenase 1 (P5CDh1) encodes a conserved, nuclear-encoded mitochondrial matrix enzyme. It is a member of the aldehyde dehydrogenase superfamily involved in proline degradation.
  
 0.979
P5cr
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; L-proline biosynthetic process.
  
 0.976
P5cr-2
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; L-proline biosynthetic process.
   
 0.955
S-Lap4
Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
     
  0.900
S-Lap1
Sperm-Leucylaminopeptidase 1; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: mushroom body development; proteolysis.
     
  0.900
S-Lap2
Sperm-Leucylaminopeptidase 2; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
     
  0.900
S-Lap8
Sperm-Leucylaminopeptidase 8; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
     
  0.900
S-Lap5
Sperm-Leucylaminopeptidase 5; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis; mesoderm development.
     
  0.900
loopin-1
Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms.
     
  0.900
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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