STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp6t1Probable cytochrome P450 6t1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (529 aa)    
Predicted Functional Partners:
Cyp304a1
Probable cytochrome P450 304a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
 0.734
CG6012
MIP25013p; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.691
Had2
Beta hydroxy acid dehydrogenase 2; 3-hydroxyacyl-CoA dehydrogenase activity. It is involved in the biological process described with: fatty acid metabolic process; oxidation-reduction process.
      
 0.661
spok
Spookier (spok) encodes a cytochrome P450 involved in ecdysteroid biosynthesis that is expressed primarily in the prothoracic gland and is localized in the endoplasmic reticulum. Genetic evidence suggests that the product of spok acts with the products of sro and Cyp6t3 to catalyze conversion of 7 dehydrocholesterol to delta4, diketol during the ecdysone biosynthetic pathway.
  
 
 0.583
shd
Ecdysone 20-monooxygenase; Shade (shd) encodes 20-hydroxylase and is responsible for converting Ecdysone into 20-hydroxyecdysone, the active form of the steroid. It is required in all tissues that produce active Ecdysone and thus contributes to larval moulting, metamorphosis, growth, neuroblast diversity and egg chamber maturation; Belongs to the cytochrome P450 family.
  
   0.538
glob2
Globin 2, isoform B; Oxygen binding; heme binding; Belongs to the globin family.
   
  
 0.517
Ugt37B1
UDP-glycosyltransferase family 37 member B1; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process.
   
 
 0.514
Ugt304A1
UDP-glycosyltransferase family 304 member A1; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
   
 
 0.507
P5cr
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; L-proline biosynthetic process.
   
  
 0.505
Ir7g
Ionotropic receptor 7g.
   
  
 0.496
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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