Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atg7 | CG17068 | FBpp0085891 | FBpp0077033 | Autophagy-related 7 (Atg7) encodes an E1-type ligase for the autophagic ubiquitin-like proteins encoded by Atg8a and Atg12. Its roles include autophagosome formation, maintaining neuromuscular function and normal lifespan. | LP10161p; It is involved in the biological process described with: neurogenesis. | 0.520 |
| Atg7 | Uba3 | FBpp0085891 | FBpp0086711 | Autophagy-related 7 (Atg7) encodes an E1-type ligase for the autophagic ubiquitin-like proteins encoded by Atg8a and Atg12. Its roles include autophagosome formation, maintaining neuromuscular function and normal lifespan. | Nedd8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric Uba3-APP-BP1 E1 enzyme. E1 activates Nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a Nedd8-Uba3 thioester and free AMP. E1 finally transfers Nedd8 to the catalytic cysteine of UbcE2M. Required for Cul1 and Cul3 neddylation. Negatively regulates full-length ci stability and hedgehog signaling. | 0.706 |
| Atg7 | UbcE2M | FBpp0085891 | FBpp0304449 | Autophagy-related 7 (Atg7) encodes an E1-type ligase for the autophagic ubiquitin-like proteins encoded by Atg8a and Atg12. Its roles include autophagosome formation, maintaining neuromuscular function and normal lifespan. | Nedd8-conjugating enzyme UbcE2M; Accepts the ubiquitin-like protein Nedd8 from the Uba3-APP- BP1 E1 complex and catalyzes its covalent attachment to other proteins. Required for Cul1 and Cul3 neddylation. Negatively regulates full- length ci stability and hedgehog signaling. | 0.804 |
| CG12106 | CG17068 | FBpp0071241 | FBpp0077033 | RE09151p; It is involved in the biological process described with: sodium ion transport. | LP10161p; It is involved in the biological process described with: neurogenesis. | 0.516 |
| CG12106 | CG9951 | FBpp0071241 | FBpp0075096 | RE09151p; It is involved in the biological process described with: sodium ion transport. | Coiled-coil domain-containing protein 22 homolog; Cullin family protein binding. It is involved in the biological process described with: positive regulation of ubiquitin-dependent protein catabolic process; Belongs to the CCDC22 family. | 0.599 |
| CG12106 | CSN3 | FBpp0071241 | FBpp0077927 | RE09151p; It is involved in the biological process described with: sodium ion transport. | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes [...] | 0.400 |
| CG12106 | CSN5 | FBpp0071241 | FBpp0082743 | RE09151p; It is involved in the biological process described with: sodium ion transport. | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of [...] | 0.403 |
| CG12106 | CSN6 | FBpp0071241 | FBpp0083658 | RE09151p; It is involved in the biological process described with: sodium ion transport. | COP9 signalosome complex subunit 6; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes [...] | 0.433 |
| CG12106 | SCCRO | FBpp0071241 | FBpp0297285 | RE09151p; It is involved in the biological process described with: sodium ion transport. | DCN1-like protein; May contribute to neddylation of cullin components of SCF- type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity). | 0.505 |
| CG12106 | Uba3 | FBpp0071241 | FBpp0086711 | RE09151p; It is involved in the biological process described with: sodium ion transport. | Nedd8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric Uba3-APP-BP1 E1 enzyme. E1 activates Nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a Nedd8-Uba3 thioester and free AMP. E1 finally transfers Nedd8 to the catalytic cysteine of UbcE2M. Required for Cul1 and Cul3 neddylation. Negatively regulates full-length ci stability and hedgehog signaling. | 0.512 |
| CG12106 | UbcE2M | FBpp0071241 | FBpp0304449 | RE09151p; It is involved in the biological process described with: sodium ion transport. | Nedd8-conjugating enzyme UbcE2M; Accepts the ubiquitin-like protein Nedd8 from the Uba3-APP- BP1 E1 complex and catalyzes its covalent attachment to other proteins. Required for Cul1 and Cul3 neddylation. Negatively regulates full- length ci stability and hedgehog signaling. | 0.499 |
| CG12106 | Vlet | FBpp0071241 | FBpp0073378 | RE09151p; It is involved in the biological process described with: sodium ion transport. | Valette, isoform B. | 0.603 |
| CG17068 | Atg7 | FBpp0077033 | FBpp0085891 | LP10161p; It is involved in the biological process described with: neurogenesis. | Autophagy-related 7 (Atg7) encodes an E1-type ligase for the autophagic ubiquitin-like proteins encoded by Atg8a and Atg12. Its roles include autophagosome formation, maintaining neuromuscular function and normal lifespan. | 0.520 |
| CG17068 | CG12106 | FBpp0077033 | FBpp0071241 | LP10161p; It is involved in the biological process described with: neurogenesis. | RE09151p; It is involved in the biological process described with: sodium ion transport. | 0.516 |
| CG17068 | CG9951 | FBpp0077033 | FBpp0075096 | LP10161p; It is involved in the biological process described with: neurogenesis. | Coiled-coil domain-containing protein 22 homolog; Cullin family protein binding. It is involved in the biological process described with: positive regulation of ubiquitin-dependent protein catabolic process; Belongs to the CCDC22 family. | 0.507 |
| CG17068 | CSN3 | FBpp0077033 | FBpp0077927 | LP10161p; It is involved in the biological process described with: neurogenesis. | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes [...] | 0.513 |
| CG17068 | CSN5 | FBpp0077033 | FBpp0082743 | LP10161p; It is involved in the biological process described with: neurogenesis. | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of [...] | 0.516 |
| CG17068 | CSN6 | FBpp0077033 | FBpp0083658 | LP10161p; It is involved in the biological process described with: neurogenesis. | COP9 signalosome complex subunit 6; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes [...] | 0.510 |
| CG17068 | SCCRO | FBpp0077033 | FBpp0297285 | LP10161p; It is involved in the biological process described with: neurogenesis. | DCN1-like protein; May contribute to neddylation of cullin components of SCF- type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity). | 0.511 |
| CG17068 | Uba3 | FBpp0077033 | FBpp0086711 | LP10161p; It is involved in the biological process described with: neurogenesis. | Nedd8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric Uba3-APP-BP1 E1 enzyme. E1 activates Nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a Nedd8-Uba3 thioester and free AMP. E1 finally transfers Nedd8 to the catalytic cysteine of UbcE2M. Required for Cul1 and Cul3 neddylation. Negatively regulates full-length ci stability and hedgehog signaling. | 0.515 |
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