STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG14621Solute carrier family 35 member E1 homolog; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. (373 aa)    
Predicted Functional Partners:
CG7785
RE37682p.
   
  
 0.837
CG31436
IP12392p.
      
 0.680
CG13248
FI04531p; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transport; amino acid transmembrane transport.
      
 0.668
NK7.1
NK7.1, isoform A; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; cell differentiation.
      
 0.663
CG17239
Uncharacterized protein, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.663
CG32850
GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination.
      
 0.661
frc
UDP-sugar transporter UST74c; Involved in the import of UDP-sugars from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35D subfamily.
      
 0.648
nac
GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling; Belongs to the TPT transporter family. SLC35C subfamily.
      
 0.645
CG1275
LD36721p; Oxidoreductase activity; ferric-chelate reductase activity; metal ion binding.
      
 0.634
sll
Slalom (sll) encodes the first transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), that transfers PAPS from cytosol into the lumen of Golgi. It contributes to the sulfation of glycans and proteins, the regulation of several signaling pathways (Hh, Wingless) mediated by glycosaminoglycans during patterning and morphogenesis, and the determination of the embryonic dorsal/ventral axis; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
   
 
 0.630
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.