node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG9915 | Eaf | FBpp0307918 | FBpp0088079 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. | ELL-associated factor (Eaf) encodes a protein interactor of the ELL homolog encoded by Su(Tpl). It increases the ability of the product of Su(Tpl) to enhance transcription elongation of RNA Polymerase II. | 0.816 |
CG9915 | Su(Tpl) | FBpp0307918 | FBpp0310656 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. | RNA polymerase II elongation factor Ell; Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III ; Belongs to the ELL/occludin family. | 0.800 |
CG9915 | TfIIS | FBpp0307918 | FBpp0304751 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. | Transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. | 0.950 |
CG9915 | hyx | FBpp0307918 | FBpp0289644 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. | Hyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. | 0.592 |
CG9915 | lilli | FBpp0307918 | FBpp0077318 | Uncharacterized protein, isoform B; It is involved in the biological process described with: regulation of mRNA export from nucleus; regulation of histone H3-K36 trimethylation; regulation of mRNA processing. | AF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation. Belongs to the AF4 [...] | 0.809 |
Cdk9 | CycT | FBpp0071848 | FBpp0305335 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | 0.999 |
Cdk9 | Eaf | FBpp0071848 | FBpp0088079 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | ELL-associated factor (Eaf) encodes a protein interactor of the ELL homolog encoded by Su(Tpl). It increases the ability of the product of Su(Tpl) to enhance transcription elongation of RNA Polymerase II. | 0.857 |
Cdk9 | Ice1 | FBpp0071848 | FBpp0071919 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | Little elongation complex subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies. Belongs to the ICE1 family. | 0.771 |
Cdk9 | Su(Tpl) | FBpp0071848 | FBpp0310656 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | RNA polymerase II elongation factor Ell; Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III ; Belongs to the ELL/occludin family. | 0.983 |
Cdk9 | TfIIS | FBpp0071848 | FBpp0304751 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | Transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. | 0.675 |
Cdk9 | ear | FBpp0071848 | FBpp0303072 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | ENL/AF9-related, isoform B; ENL/AF9-related (ear) encodes a transcription factor that is a component of the super elongation complex (SEC), which regulates transcription by RNA Polymerase II. It also interacts with the histone methyltransferase encoded by gpp in the Dot1 complex (DotCom), which modifies chromatin structure by methylating histone H3 on lysine 79. | 0.990 |
Cdk9 | hyx | FBpp0071848 | FBpp0289644 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | Hyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. | 0.965 |
Cdk9 | lilli | FBpp0071848 | FBpp0077318 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | AF4/FMR2 family member lilli; Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation. Belongs to the AF4 [...] | 0.989 |
Cdk9 | trx | FBpp0071848 | FBpp0082406 | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | Histone-lysine N-methyltransferase trithorax; Histone methyltransferase that trimethylates 'Lys-9' of histone H3 (H3K9me3). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo. | 0.807 |
CycT | Cdk9 | FBpp0305335 | FBpp0071848 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | Positive transcription elongation factor b small subunit; Cyclin-dependent kinase 9 (Cdk9) encodes a cyclin dependent kinase that along with the product of CycT forms the positive transcription elongation factor, which is involved in RNA polymerase II elongation control. | 0.999 |
CycT | Eaf | FBpp0305335 | FBpp0088079 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | ELL-associated factor (Eaf) encodes a protein interactor of the ELL homolog encoded by Su(Tpl). It increases the ability of the product of Su(Tpl) to enhance transcription elongation of RNA Polymerase II. | 0.831 |
CycT | Ice1 | FBpp0305335 | FBpp0071919 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | Little elongation complex subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies. Belongs to the ICE1 family. | 0.799 |
CycT | Su(Tpl) | FBpp0305335 | FBpp0310656 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | RNA polymerase II elongation factor Ell; Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III ; Belongs to the ELL/occludin family. | 0.955 |
CycT | TfIIS | FBpp0305335 | FBpp0304751 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | Transcription elongation factor S-II; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. | 0.523 |
CycT | ear | FBpp0305335 | FBpp0303072 | Cyclin-T; Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy- terminal domain) of the large subunit of RNA polymerase II (RNAP II). | ENL/AF9-related, isoform B; ENL/AF9-related (ear) encodes a transcription factor that is a component of the super elongation complex (SEC), which regulates transcription by RNA Polymerase II. It also interacts with the histone methyltransferase encoded by gpp in the Dot1 complex (DotCom), which modifies chromatin structure by methylating histone H3 on lysine 79. | 0.920 |