Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG17234Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (251 aa)    
Predicted Functional Partners:
Send2
Spermathecal endopeptidase 2; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.968
CG14191
Uncharacterized protein.
    
 
 0.657
CG17239
Uncharacterized protein, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.619
CG31324
HL03650p.
      
 0.598
GILT2
GILT-like protein 2; Gamma-interferon-inducible lysosomal thiol reductase 2 (GILT2) encodes a unique thiol reductase that catalyzes the disulfide bond reduction. It is involved in immune response against bacterial and viral challenge via JAK-STAT signaling pathway; Belongs to the GILT family.
    
 
 0.529
CG34290
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.528
CG11668
LP04014p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.526
Nep7
Neprilysin 7; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.520
Listericin
GEO12728p1; Listericin (Listericin) encodes an antibacterial protein whose induction is cooperatively regulated by the product of PGRP-LE and the JAK-STAT pathway.
      
 0.520
Mal-B1
Maltase B1; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
      
 0.519
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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