STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oafOut at first short protein; Vital for proper neuronal development and hatching; Belongs to the OAF family. (487 aa)    
Predicted Functional Partners:
Df31
Decondensation factor 31 (Df31) encodes a histone binding protein involved in nucleosome assembly.
   
  
 0.679
inaE
Inactivation no afterpotential E (inaE) encodes a diacylglycerol lipase involved in phototransduction and response to oxidative stress.
   
  
 0.660
cbt
Cabut, isoform A; Cabut (cbt) encodes a transcription factor that controls Dpp signaling and is involved in dorsal closure and wing disc morphogenesis.
   
  
 0.605
CG9008
Glucose-6-phosphate 1-epimerase activity; carbohydrate binding. It is involved in the biological process described with: defense response to virus; carbohydrate metabolic process.
      
 0.604
CG3556
Uncharacterized protein CG3556; Cobalamin binding. It is involved in the biological process described with: cobalamin transport.
      
 0.530
ave
Protein aveugle; Required for normal photoreceptor differentiation between Ras and Raf for EGFR signaling in the eye and for mitogen-activated protein kinase phosphorylation. Probably acts together with Cnk to promote Raf activation, perhaps by recruiting an activating kinase.
      
 0.495
Rrp40
Ribosomal RNA processing 40 (Rrp40) encodes a protein involved in gene expression regulation.
      
 0.432
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.