STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Got2Aspartate aminotransferase; Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. (431 aa)    
Predicted Functional Partners:
CG1640
AT04676p; Pyridoxal phosphate binding; L-alanine:2-oxoglutarate aminotransferase activity. It is involved in the biological process described with: biosynthetic process.
   
 0.996
Mdh2
Malate dehydrogenase 2 (Mdh2) encodes one of the enzymes in the tricarboxylic acid cycle in mitochondria; Belongs to the LDH/MDH superfamily.
   
 0.989
Ldh
Lactate dehydrogenase (Ldh) encodes a protein involved in myoblast fusion and somatic muscle development; Belongs to the LDH/MDH superfamily. LDH family.
   
 0.989
Mdh1
Malate dehydrogenase 1 (Mdh1) encodes a L-malate dehydrogenase involved in the interconversion of malate and oxaloacetate.
   
 0.988
Got1
Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis.
  
0.984
CG1461
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 0.981
Gdh
Glutamate dehydrogenase, mitochondrial; Glutamate dehydrogenase (Gdh) encodes a glutamate dehydrogenase involved glutamate metabolism.
   
 0.974
Hpd
4-hydroxyphenylpyruvate dioxygenase activity. It is involved in the biological process described with: oxidation-reduction process; tyrosine catabolic process.
  
 
 0.968
CG10749
L-malate dehydrogenase activity. It is involved in the biological process described with: carbohydrate metabolic process; malate metabolic process; tricarboxylic acid cycle.
   
 0.967
CG10748
L-malate dehydrogenase activity. It is involved in the biological process described with: tricarboxylic acid cycle; malate metabolic process; carbohydrate metabolic process.
   
 0.967
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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