Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CG31937IP05441p; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)    
Predicted Functional Partners:
Rrp40
Ribosomal RNA processing 40 (Rrp40) encodes a protein involved in gene expression regulation.
 
  
   0.839
smid
Smallminded, isoform A; Preribosome binding; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of telomerase activity; ribosome biogenesis.
    
 
 0.685
CG12301
LD31322p; It is involved in the biological process described with: rRNA processing; mushroom body development.
      
 0.589
CG7289
LD12115p.
      
 0.462
Ldsdh1
Lipid droplet subset dehydrogenase 1; Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; retinol dehydrogenase activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.455
Sec61alpha
Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel.
   
 
 0.450
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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