Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG12717 | frtz | FBpp0311949 | FBpp0077577 | FI06413p; SUMO-specific isopeptidase activity; SUMO-specific endopeptidase activity. It is involved in the biological process described with: dendritic spine morphogenesis; central nervous system projection neuron axonogenesis; protein desumoylation. | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | 0.603 |
| Mks1 | frtz | FBpp0073500 | FBpp0077577 | Meckel syndrome type 1 protein homolog; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function. | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | 0.527 |
| Rab23 | frtz | FBpp0078376 | FBpp0077577 | RH23273p; Rab23 (Rab23) encodes a member of the Rab family of small GTPases known to be involved in vesicle transport processes. It cooperates with the product of in and the core group of planar cell polarity genes. It contributes to restricting actin accumulation and thus, prehair initiation to a single site within each wing cell, and to regulate the number and orientation of hairs on the leg and the abdominal cuticle. In addition, it regulates the trafficking of the ligand encoded by hh in the germline stem cell niche. | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | 0.591 |
| Rab23 | fy | FBpp0078376 | FBpp0079317 | RH23273p; Rab23 (Rab23) encodes a member of the Rab family of small GTPases known to be involved in vesicle transport processes. It cooperates with the product of in and the core group of planar cell polarity genes. It contributes to restricting actin accumulation and thus, prehair initiation to a single site within each wing cell, and to regulate the number and orientation of hairs on the leg and the abdominal cuticle. In addition, it regulates the trafficking of the ligand encoded by hh in the germline stem cell niche. | Protein fuzzy; Plays a role in the organization of cell polarity via a planar cell polarity (PCP) cascade. Involved in the development of the hairs on the wings. Specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cells. Controls wing cell hair number by maintaining the integrity of the cytoskeletal components that direct hair development. Belongs to the fuzzy family. | 0.545 |
| Rab23 | in | FBpp0078376 | FBpp0077841 | RH23273p; Rab23 (Rab23) encodes a member of the Rab family of small GTPases known to be involved in vesicle transport processes. It cooperates with the product of in and the core group of planar cell polarity genes. It contributes to restricting actin accumulation and thus, prehair initiation to a single site within each wing cell, and to regulate the number and orientation of hairs on the leg and the abdominal cuticle. In addition, it regulates the trafficking of the ligand encoded by hh in the germline stem cell niche. | Inturned (in) encodes a cytoplasmic protein that functions as a downstream member of the fz-stan planar cell polarity pathway, which controls hair and bristle polarity in the adult. In directly binds with the products of fy, frtz and mwh and accumulates on the proximal side of wing cells. | 0.685 |
| Zfrp8 | frtz | FBpp0072162 | FBpp0077577 | Zinc finger protein RP-8 (Zfrp8) encodes a highly conserved protein essential for stem cell maintenance and fast proliferating cells such as cancer cells. It functions in the formation of mRNA ribonucleoprotein (mRNP) complexes. It may regulate the binding of specific mRNPs to the small ribosomal subunit, ultimately controlling their cytoplasmic localization and translation. | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | 0.568 |
| Zfrp8 | trus | FBpp0072162 | FBpp0082103 | Zinc finger protein RP-8 (Zfrp8) encodes a highly conserved protein essential for stem cell maintenance and fast proliferating cells such as cancer cells. It functions in the formation of mRNA ribonucleoprotein (mRNP) complexes. It may regulate the binding of specific mRNPs to the small ribosomal subunit, ultimately controlling their cytoplasmic localization and translation. | Toys are us. | 0.452 |
| cort | frtz | FBpp0078949 | FBpp0077577 | Protein cortex; Female meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C). Required for the completion of meiosis in oocytes. Activates the ubiquitin ligase activity and substrate specificity of APC/C and triggers the sequential degradation of mitotic cyclins in meiosis. Promotes the ubiquitination and degradation of CycA early in meiosis I and the degradation of CycB and CycB3 after egg activation. Promotes degradation of mtrm at the oocyte-to-embryo transition. Belongs to the WD repeat CORT family. | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | 0.521 |
| cort | fzr | FBpp0078949 | FBpp0070654 | Protein cortex; Female meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C). Required for the completion of meiosis in oocytes. Activates the ubiquitin ligase activity and substrate specificity of APC/C and triggers the sequential degradation of mitotic cyclins in meiosis. Promotes the ubiquitination and degradation of CycA early in meiosis I and the degradation of CycB and CycB3 after egg activation. Promotes degradation of mtrm at the oocyte-to-embryo transition. Belongs to the WD repeat CORT family. | Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase. | 0.576 |
| cort | fzy | FBpp0078949 | FBpp0080391 | Protein cortex; Female meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C). Required for the completion of meiosis in oocytes. Activates the ubiquitin ligase activity and substrate specificity of APC/C and triggers the sequential degradation of mitotic cyclins in meiosis. Promotes the ubiquitination and degradation of CycA early in meiosis I and the degradation of CycB and CycB3 after egg activation. Promotes degradation of mtrm at the oocyte-to-embryo transition. Belongs to the WD repeat CORT family. | FI02843p; Fizzy (fzy) encodes WD40 domain protein required for the full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) in mitosis and meiosis. The product of fzy functions to target substrates for destruction and drive metaphase and anaphase transition. | 0.567 |
| frtz | CG12717 | FBpp0077577 | FBpp0311949 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | FI06413p; SUMO-specific isopeptidase activity; SUMO-specific endopeptidase activity. It is involved in the biological process described with: dendritic spine morphogenesis; central nervous system projection neuron axonogenesis; protein desumoylation. | 0.603 |
| frtz | Mks1 | FBpp0077577 | FBpp0073500 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Meckel syndrome type 1 protein homolog; Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia. Required for ciliary structure and function. | 0.527 |
| frtz | Rab23 | FBpp0077577 | FBpp0078376 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | RH23273p; Rab23 (Rab23) encodes a member of the Rab family of small GTPases known to be involved in vesicle transport processes. It cooperates with the product of in and the core group of planar cell polarity genes. It contributes to restricting actin accumulation and thus, prehair initiation to a single site within each wing cell, and to regulate the number and orientation of hairs on the leg and the abdominal cuticle. In addition, it regulates the trafficking of the ligand encoded by hh in the germline stem cell niche. | 0.591 |
| frtz | Zfrp8 | FBpp0077577 | FBpp0072162 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Zinc finger protein RP-8 (Zfrp8) encodes a highly conserved protein essential for stem cell maintenance and fast proliferating cells such as cancer cells. It functions in the formation of mRNA ribonucleoprotein (mRNP) complexes. It may regulate the binding of specific mRNPs to the small ribosomal subunit, ultimately controlling their cytoplasmic localization and translation. | 0.568 |
| frtz | cort | FBpp0077577 | FBpp0078949 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Protein cortex; Female meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C). Required for the completion of meiosis in oocytes. Activates the ubiquitin ligase activity and substrate specificity of APC/C and triggers the sequential degradation of mitotic cyclins in meiosis. Promotes the ubiquitination and degradation of CycA early in meiosis I and the degradation of CycB and CycB3 after egg activation. Promotes degradation of mtrm at the oocyte-to-embryo transition. Belongs to the WD repeat CORT family. | 0.521 |
| frtz | fy | FBpp0077577 | FBpp0079317 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Protein fuzzy; Plays a role in the organization of cell polarity via a planar cell polarity (PCP) cascade. Involved in the development of the hairs on the wings. Specify the correct orientation of the hair by limiting the site of prehair initiation to the distal vertex of the wing cells. Controls wing cell hair number by maintaining the integrity of the cytoskeletal components that direct hair development. Belongs to the fuzzy family. | 0.814 |
| frtz | fzr | FBpp0077577 | FBpp0070654 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase. | 0.521 |
| frtz | fzy | FBpp0077577 | FBpp0080391 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | FI02843p; Fizzy (fzy) encodes WD40 domain protein required for the full ubiquitin ligase activity of the anaphase-promoting complex/cyclosome (APC/C) in mitosis and meiosis. The product of fzy functions to target substrates for destruction and drive metaphase and anaphase transition. | 0.521 |
| frtz | in | FBpp0077577 | FBpp0077841 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Inturned (in) encodes a cytoplasmic protein that functions as a downstream member of the fz-stan planar cell polarity pathway, which controls hair and bristle polarity in the adult. In directly binds with the products of fy, frtz and mwh and accumulates on the proximal side of wing cells. | 0.965 |
| frtz | trus | FBpp0077577 | FBpp0082103 | Fritz (frtz) encodes a cytoplasmic protein that functions as a planar polarity effector as a downstream member of the fz-stan planar cell polarity pathway that controls hair and bristle polarity. frtz protein directly binds to the product of in and accumulates on the proximal side of wing cells. | Toys are us. | 0.568 |
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