STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3862Uncharacterized protein. (454 aa)    
Predicted Functional Partners:
CG8671
Uncharacterized protein, isoform A; It is involved in the biological process described with: dsRNA transport.
      
 0.912
nito
RNA-binding protein spenito; RNA-binding protein that acts as an associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs. M6a modification plays a role in the efficiency of mRNA splicing and is required for sex determination. In the WMM complex, may act by binding target RNAs and recruiting the WMM complex. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physi [...]
      
 0.891
CG15107
Uncharacterized protein, isoform B.
   
  
 0.837
regucalcin
Regucalcin, isoform D; Calcium ion binding; gluconolactonase activity. It is involved in the biological process described with: L-ascorbic acid biosynthetic process; multicellular organism reproduction.
   
  
 0.741
CG13585
MIP15530p.
      
 0.616
CG13397
LP03571p; alpha-N-acetylglucosaminidase activity.
      
 0.608
CG8507
LD29322p; Heparin binding; low-density lipoprotein particle receptor binding; receptor antagonist activity. It is involved in the biological process described with: regulation of receptor-mediated endocytosis.
      
 0.602
PrBP
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; 3',5'-cyclic-nucleotide phosphodiesterase activity; protein binding. It is involved in the biological process described with: mushroom body development; sensory perception of light stimulus.
    
 
 0.598
mt:ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 
 0.581
CG40191
RE22570p; Cyclin-dependent protein serine/threonine kinase regulator activity. It is involved in the biological process described with: regulation of cyclin-dependent protein serine/threonine kinase activity.
      
 0.573
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.