STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11885GEO08637p1. (141 aa)    
Predicted Functional Partners:
CG13319
GH19585p; It is involved in the biological process described with: proteasome assembly.
   
 
 0.974
CG12321
Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family.
   
 
 0.973
PSMG1
GH13924p; Proteasome binding. It is involved in the biological process described with: proteasome core complex assembly.
   
 
 0.824
Pomp
GEO05038p1; It is involved in the biological process described with: proteasome assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteolysis.
   
 
 0.708
Prosalpha2
Proteasome subunit alpha type-2; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
   
   0.649
GNBP2
Gram-negative bacteria-binding protein 2; Involved in the recognition of invading micro-organisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity); Belongs to the insect beta-1,3-glucan binding protein family.
      
 0.628
Prosalpha5
Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family.
   
 
 0.586
CG13994
GEO08832p1; Protein phosphatase 1 binding; ubiquitin protein ligase activity; protein serine/threonine phosphatase inhibitor activity. It is involved in the biological process described with: negative regulation of protein dephosphorylation; negative regulation of phosphoprotein phosphatase activity; defense response to Gram-negative bacterium; ubiquitin-dependent protein catabolic process; positive regulation of innate immune response.
   
  
 0.578
Pfdn5
Probable prefoldin subunit 5; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit alpha family.
   
  
 0.547
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase activity. It is involved in the biological process described with: phosphatidic acid biosynthetic process; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
      
 0.533
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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