STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
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[Homology]
Score
CG3709Putative tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase Pus10 family. (500 aa)    
Predicted Functional Partners:
Pus7
Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: pseudouridine synthesis.
   
  
 0.957
CG11837
Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
  
  
 0.904
Pus1
Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: tRNA pseudouridine synthesis; mRNA pseudouridine synthesis.
   
  
 0.876
CG13694
Uncharacterized protein, isoform A.
      
 0.790
CG42399
Uncharacterized protein, isoform B; Microtubule binding. It is involved in the biological process described with: microtubule cytoskeleton organization.
      
 0.790
CG31975
Uncharacterized protein, isoform B.
      
 0.790
CG9288
Protein Abitram; May regulate actin polymerization.
   
   0.783
CG7637
H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity); Belongs to the NOP10 family.
  
  
 0.683
CG11377
RE58433p; Calcium ion binding.
   
  
 0.671
CG11454
RRM domain-containing protein; mRNA binding; single-stranded RNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome.
   
  
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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