STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mst77FHistone-like protein 18C; Not known. Encoded in the intron of cAMP-dependent protein kinase regulatory chain type I. (215 aa)    
Predicted Functional Partners:
ProtA
Protamine A (ProtA) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines.
   
  
 0.985
CG3213
FI13205p.
   
    0.980
S-Lap7
Sperm-Leucylaminopeptidase 7, isoform A; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction.
   
    0.970
ProtB
Protamine B (ProtB) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines.
   
  
 0.968
CG14926
CG14926 protein.
   
    0.952
Mst84Db
It is involved in the biological process described with: spermatogenesis; sperm axoneme assembly.
   
  
 0.948
Prtl99C
Protamine-like 99C (Prtl99C) encodes a sperm chromatin-associated protein that is essential for male fertility. It acts additively together with the products of Mst77F, ProtA and ProtB to compact the paternal chromatin; Belongs to the UPF0771 family.
   
  
 0.927
betaTub85D
Tubulin beta-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family.
   
  
 0.915
tHMG1
Testis-enriched HMG-box-containing protein 1 (tHMG1) encodes a chromosomal protein involved in spermatogenesis.
   
  
 0.913
Tpl94D
Transition protein-like 94D (Tpl94D) encodes a HMG-box domain protein that is expressed during chromatin reorganization in spermatids.
   
  
 0.904
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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