| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG10778 | CG17565 | FBpp0071083 | FBpp0082737 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | 0.975 |
| CG10778 | Coq2 | FBpp0071083 | FBpp0081347 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 0.512 |
| CG10778 | Fpps | FBpp0071083 | FBpp0087266 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | Farnesyl pyrophosphate synthase (Fpps) encodes a protein involved in germ cell migration; Belongs to the FPP/GGPP synthase family. | 0.977 |
| CG10778 | Pdss2 | FBpp0071083 | FBpp0077945 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | Decaprenyl diphosphate synthase subunit 2, isoform A; Prenyltransferase activity; trans-hexaprenyltranstransferase activity. It is involved in the biological process described with: isoprenoid biosynthetic process; ubiquinone biosynthetic process; Belongs to the FPP/GGPP synthase family. | 0.937 |
| CG10778 | qless | FBpp0071083 | FBpp0085131 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | Qless, isoform A; Qless (qless) encodes a protein involved in the synthesis of the isoprenoid side chain of Coenzyme Q, a lipid component of the mitochondrial electron transport chain; Belongs to the FPP/GGPP synthase family. | 0.942 |
| CG10778 | qm | FBpp0071083 | FBpp0291255 | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | Quemao, isoform A; Quemao (qm) encodes the ortholog of human geranylgeranyl pyrophosphate synthase (GGPS1), which catalyses protein prenylation and thereby facilitates membrane targeting of proteins. The qm product contributes to heart formation, germ cell migration, and maintenance of plasma membrane integrity in growing oocytes. | 0.945 |
| CG17565 | CG10778 | FBpp0082737 | FBpp0071083 | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | 0.975 |
| CG17565 | Fpps | FBpp0082737 | FBpp0087266 | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | Farnesyl pyrophosphate synthase (Fpps) encodes a protein involved in germ cell migration; Belongs to the FPP/GGPP synthase family. | 0.981 |
| CG17565 | Pdss2 | FBpp0082737 | FBpp0077945 | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | Decaprenyl diphosphate synthase subunit 2, isoform A; Prenyltransferase activity; trans-hexaprenyltranstransferase activity. It is involved in the biological process described with: isoprenoid biosynthetic process; ubiquinone biosynthetic process; Belongs to the FPP/GGPP synthase family. | 0.932 |
| CG17565 | qless | FBpp0082737 | FBpp0085131 | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | Qless, isoform A; Qless (qless) encodes a protein involved in the synthesis of the isoprenoid side chain of Coenzyme Q, a lipid component of the mitochondrial electron transport chain; Belongs to the FPP/GGPP synthase family. | 0.952 |
| CG17565 | qm | FBpp0082737 | FBpp0291255 | Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. | Quemao, isoform A; Quemao (qm) encodes the ortholog of human geranylgeranyl pyrophosphate synthase (GGPS1), which catalyses protein prenylation and thereby facilitates membrane targeting of proteins. The qm product contributes to heart formation, germ cell migration, and maintenance of plasma membrane integrity in growing oocytes. | 0.953 |
| Coq2 | CG10778 | FBpp0081347 | FBpp0071083 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Alkyl transferase; Dehydrodolichyl diphosphate synthase activity; polyprenyltransferase activity. It is involved in the biological process described with: polyprenol biosynthetic process; Belongs to the UPP synthase family. | 0.512 |
| Coq2 | Coq4 | FBpp0081347 | FBpp0289097 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. | 0.969 |
| Coq2 | Coq5 | FBpp0081347 | FBpp0311954 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.969 |
| Coq2 | Coq6 | FBpp0081347 | FBpp0078759 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.991 |
| Coq2 | Coq8 | FBpp0081347 | FBpp0073530 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Coenzyme Q8; Protein kinase activity; kinase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; ubiquinone biosynthetic process. | 0.969 |
| Coq2 | Fpps | FBpp0081347 | FBpp0087266 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Farnesyl pyrophosphate synthase (Fpps) encodes a protein involved in germ cell migration; Belongs to the FPP/GGPP synthase family. | 0.593 |
| Coq2 | Pdss2 | FBpp0081347 | FBpp0077945 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Decaprenyl diphosphate synthase subunit 2, isoform A; Prenyltransferase activity; trans-hexaprenyltranstransferase activity. It is involved in the biological process described with: isoprenoid biosynthetic process; ubiquinone biosynthetic process; Belongs to the FPP/GGPP synthase family. | 0.993 |
| Coq2 | qless | FBpp0081347 | FBpp0085131 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Qless, isoform A; Qless (qless) encodes a protein involved in the synthesis of the isoprenoid side chain of Coenzyme Q, a lipid component of the mitochondrial electron transport chain; Belongs to the FPP/GGPP synthase family. | 0.965 |
| Coq2 | qm | FBpp0081347 | FBpp0291255 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Quemao, isoform A; Quemao (qm) encodes the ortholog of human geranylgeranyl pyrophosphate synthase (GGPS1), which catalyses protein prenylation and thereby facilitates membrane targeting of proteins. The qm product contributes to heart formation, germ cell migration, and maintenance of plasma membrane integrity in growing oocytes. | 0.662 |