STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12975Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both RNA and protein methyltransferases. (124 aa)    
Predicted Functional Partners:
HemK2
HemK methyltransferase 2; Protein methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
   
 0.999
CG17807
Fe2OG dioxygenase domain-containing protein; Nucleic acid binding; tRNA (uracil) methyltransferase activity; 2-oxoglutarate-dependent dioxygenase activity. It is involved in the biological process described with: tRNA methylation; oxidation-reduction process; tRNA wobble uridine modification.
   
 
 0.997
CG10903
RE22146p; rRNA (guanine) methyltransferase activity. It is involved in the biological process described with: rRNA (guanine-N7)-methylation.
   
 
 0.994
CG9666
LD25448p2; Methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
   
 
 0.994
CG1074
SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation.
   
 
 0.960
fid
Fire dancer (fid) encodes a protein involved in heat resistance.
   
 
 0.929
HemK1
HemK methyltransferase 1, isoform A; Protein methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: protein methylation.
    
 
 0.912
CG2972
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 
 0.907
CG6073
Protein HGH1 homolog; Belongs to the HGH1 family.
   
  
 0.881
CG32278
GH26392p.
   
 
 0.845
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.