Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CRIFCR6-interacting factor (CRIF) encodes a protein that may play a role in regulating the RNAi pathway by stabilizing the RNAase III enzyme encoded by Dcr-2. (232 aa)    
Predicted Functional Partners:
mRpL30
Mitochondrial ribosomal protein L30; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
 
 0.989
mRpL47
Mitochondrial ribosomal protein L47; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
   
 
 0.978
mRpL11
39S ribosomal protein L11, mitochondrial; Structural constituent of ribosome; large ribosomal subunit rRNA binding; rRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.977
mRpL49
Probable 39S ribosomal protein L49, mitochondrial; Structural constituent of ribosome; translation initiation factor activity. It is involved in the biological process described with: translational initiation; mitochondrial translation; Belongs to the mitochondrion-specific ribosomal protein mL49 family.
   
 
 0.972
mRpL40
Mitochondrial ribosomal protein L40; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
   
 
 0.969
mRpL42
Mitochondrial ribosomal protein L42, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
 
 0.966
mRpL41
39S ribosomal protein L41, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation; Belongs to the mitochondrion-specific ribosomal protein mL41 family.
   
 
 0.965
mRpL22
39S ribosomal protein L22, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; ribosome assembly; translation; Belongs to the universal ribosomal protein uL22 family.
   
 
 0.957
mRpL24
Probable 39S ribosomal protein L24, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation; Belongs to the universal ribosomal protein uL24 family.
   
 
 0.957
mRpL20
Mitochondrial ribosomal protein L20; rRNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the bacterial ribosomal protein bL20 family.
   
 
 0.952
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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