Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG9389GH15479p; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation. (596 aa)    
Predicted Functional Partners:
Pis
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content (By similarity). The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). Required for the regeneration of the signaling molecule phosphatidylinositol 4,5- bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing [...]
  
 
 0.933
Inos
Inositol-3-phosphate synthase activity. It is involved in the biological process described with: inositol biosynthetic process; phospholipid biosynthetic process.
  
 
 0.933
CG6910
RH44796p; Inositol oxygenase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; inositol catabolic process.
     
 0.915
CG42271
Uncharacterized protein, isoform C; Phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity.
   
 
 0.914
Ipp
Inositol polyphosphate 1-phosphatase (Ipp) encodes a protein involved in synaptic transmission and inositol metabolism regulation.
    
 0.912
CG4836
Uncharacterized protein, isoform E; L-iditol 2-dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; sorbitol catabolic process.
  
  
 0.902
Ppi1
Protein phosphatase 1 binding.
   
  
 0.880
CG4701
FI08533p; ATP binding; Belongs to the AAA ATPase family.
   
  
 0.869
Ppm1
AT28366p; Cation binding; protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation.
   
  
 0.857
CG31542
AT15479p.
   
  
 0.851
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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