STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sec20IP18173p; SNAP receptor activity. It is involved in the biological process described with: endoplasmic reticulum membrane fusion; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. (227 aa)    
Predicted Functional Partners:
Sec22
Secretory 22, isoform B; Secretory 22 (Sec22) encodes a protein involved in Wnt protein secretion; Belongs to the synaptobrevin family.
    
 0.958
Use1
Vesicle transport protein USE1; SNARE that may be involved in targeting and fusion of Golgi- derived retrograde transport vesicles with the ER (By similarity). Required for protein secretion.
   
 0.948
Syx18
Syntaxin 18 (Syx18) encodes a SNAP receptor involved in neuromuscular synaptic transmission.
   
 0.911
Syx5
Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.
   
 0.849
Snap29
Synaptosomal-associated protein 29kDa (Snap29) encodes a member of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family. It is involved in regulation of autophagy, endocytic recycling and cell division.
   
  0.821
Snap24
Synaptosomal-associated protein; SNAP receptor activity; syntaxin binding; Belongs to the SNAP-25 family.
   
  0.815
Vti1a
Vesicle transport through interaction with t-SNAREs 1a (Vti1a) encodes a protein involved in vesicle trafficking.
   
 0.812
Bet1
Blocked early in transport 1, isoform A; SNAP receptor activity; syntaxin binding. It is involved in the biological process described with: vesicle fusion with Golgi apparatus; vesicle-mediated transport; protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport.
   
  0.805
Syx8
Syntaxin 8; SNAP receptor activity; SNARE binding. It is involved in the biological process described with: intracellular protein transport; synaptic vesicle docking; vesicle fusion; vesicle docking.
    
  0.804
Membrin
Probable Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
   
  0.804
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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