Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Xe7Xe7, isoform A; Xe7 (Xe7) encodes a protein that contributes to axon guidance and lateral inhibition. (783 aa)    
Predicted Functional Partners:
CG32176
Uncharacterized protein; It is involved in the biological process described with: negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
   
   0.823
Ude
Uracil-DNA degrading factor, isoform B; Uracil-DNA degrading factor (Ude) encodes a DNA-processing enzyme with uracil-DNA-degrading activity.
   
   0.823
mRpL30
Mitochondrial ribosomal protein L30; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
      
 0.804
Evi5
Ecotropic viral integration site 5 ortholog; Functions as a GTPase-activating protein (GAP). During border cell migration in the ovary, acts as a GAP for Rab11 and is necessary for the maintenance of active receptor tyrosine kinases at the leading edge.
      
 0.769
CG5116
FI04601p; Ribosome binding; GTP binding.
   
  
 0.679
CG9773
Protein unc-50 homolog; May be required for cell surface expression of acetylcholine receptors; Belongs to the unc-50 family.
      
 0.677
RnpS1
RNA-binding protein S1 (RnpS1) encodes a protein involved in RNA splicing and regulation of DNA transposition.
    
   0.640
POSH
Plenty of SH3s (POSH) encodes a scaffold protein that regulates TNF-JNK signaling pathway.
    
 
 0.617
CG4511
GM03430p.
      
 0.612
CG9515
Uncharacterized protein, isoform A; Nucleoside-triphosphate diphosphatase activity.
      
 0.605
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.