Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Sccpdh1Saccheropin dehydrogenase 1, isoform A; Oxidoreductase activity. It is involved in the biological process described with: glycolipid biosynthetic process; oxidation-reduction process. (430 aa)    
Predicted Functional Partners:
CG31644
Uncharacterized protein, isoform C; Cytochrome-c oxidase activity.
      
 0.818
SdhAL
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
     
 0.780
CG7834
Uncharacterized protein, isoform A; Electron transfer activity. It is involved in the biological process described with: oxidative phosphorylation.
   
  
 0.672
cDIP
Common Dpr-interacting protein.
   
  
 0.656
Cyp4ac3
Probable cytochrome P450 4ac3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
      
 0.654
CG11825
Uncharacterized protein, isoform C; It is involved in the biological process described with: mitochondrial respirasome assembly; copper ion homeostasis.
      
 0.599
ATPsynbetaL
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
      
 0.593
Prx2540-1
Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis.
      
 0.592
ND-75
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...]
   
  
 0.564
CG5027
LD24073p; Thiol oxidase activity. It is involved in the biological process described with: peptidyl-cysteine oxidation; cell redox homeostasis.
      
 0.529
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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