laf protein (Drosophila melanogaster) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

laf

Labial associated factor, isoform B. (755 aa)

Predicted Functional Partners:

Trf4

0.675

Hil

0.660

Bro

0.524

CG13243

0.524

CG3123

0.511

CG15580

0.504

Opbp

0.463

CG32228

0.453

asf1

0.446

ms(2)34Fe

0.446

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bro	Hil	FBpp0072643	FBpp0085567	Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation.	Hillarin (Hil) encodes a W180-domain protein that affects cytokinesis through interactions with the Septin family member encoded by pnut in the developing nervous system; Belongs to the transglutaminase-like superfamily.	0.553
Bro	laf	FBpp0072643	FBpp0311429	Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation.	Labial associated factor, isoform B.	0.524
CG13243	laf	FBpp0303714	FBpp0311429	AT09889p.	Labial associated factor, isoform B.	0.524
CG15580	Trf4	FBpp0078270	FBpp0077384	FI16513p1.	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	0.458
CG15580	laf	FBpp0078270	FBpp0311429	FI16513p1.	Labial associated factor, isoform B.	0.504
CG15580	ms(2)34Fe	FBpp0078270	FBpp0080196	FI16513p1.	Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.	0.406
CG3123	CG32228	FBpp0077407	FBpp0074605	FI08407p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.	Uncharacterized protein.	0.471
CG3123	Trf4	FBpp0077407	FBpp0077384	FI08407p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	0.426
CG3123	laf	FBpp0077407	FBpp0311429	FI08407p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.	Labial associated factor, isoform B.	0.511
CG32228	CG3123	FBpp0074605	FBpp0077407	Uncharacterized protein.	FI08407p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.	0.471
CG32228	Trf4	FBpp0074605	FBpp0077384	Uncharacterized protein.	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	0.586
CG32228	laf	FBpp0074605	FBpp0311429	Uncharacterized protein.	Labial associated factor, isoform B.	0.453
CG32228	ms(2)34Fe	FBpp0074605	FBpp0080196	Uncharacterized protein.	Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.	0.776
Hil	Bro	FBpp0085567	FBpp0072643	Hillarin (Hil) encodes a W180-domain protein that affects cytokinesis through interactions with the Septin family member encoded by pnut in the developing nervous system; Belongs to the transglutaminase-like superfamily.	Brother (Bro) encodes a beta-subunit of the transcription factor complex core binding factor, which is involved in transcription regulation. It regulates hemocyte proliferation and acts redundantly with the product of Bgb in embryonic segmentation.	0.553
Hil	laf	FBpp0085567	FBpp0311429	Hillarin (Hil) encodes a W180-domain protein that affects cytokinesis through interactions with the Septin family member encoded by pnut in the developing nervous system; Belongs to the transglutaminase-like superfamily.	Labial associated factor, isoform B.	0.660
Opbp	laf	FBpp0085444	FBpp0311429	Optix-binding protein (Opbp) encodes a Zn finger protein that can bind to the Six-family transcription factor encoded by Optix.	Labial associated factor, isoform B.	0.463
Trf4	CG15580	FBpp0077384	FBpp0078270	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	FI16513p1.	0.458
Trf4	CG3123	FBpp0077384	FBpp0077407	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	FI08407p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.	0.426
Trf4	CG32228	FBpp0077384	FBpp0074605	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	Uncharacterized protein.	0.586
Trf4	laf	FBpp0077384	FBpp0311429	RT01008p; Transcription factor binding; RNA polymerase III regulatory region DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: transcription by RNA polymerase II; RNA polymerase III preinitiation complex assembly.	Labial associated factor, isoform B.	0.675