STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9804Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity). (234 aa)    
Predicted Functional Partners:
Las
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family.
 
 0.998
CG44243
LD05679p; Lipoyltransferase activity. It is involved in the biological process described with: protein lipoylation.
   
 0.966
ND-ACP
Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity); Belongs to the acyl carrier protein (ACP) family.
  
 0.947
CG16935
Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  
 
 0.887
CG12170
3-oxoacyl-[acyl-carrier-protein] synthase activity. It is involved in the biological process described with: fatty acid biosynthetic process; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.868
ppl
Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity); Belongs to the GcvH family.
   
 0.863
scramb2
Scramblase 2 (scramb2) encodes a protein that, together with the product of scramb1, has a modulatory function in the process of neurotransmission. They have a significant role in scrambling of phospholipids across the plasma membrane during apoptosis.
      
 0.839
scramb1
Scramblase 1 (scramb1) encodes a protein that, together with the product of scramb2, has a modulatory function in the process of neurotransmission. They have a significant role in scrambling of phospholipids across the plasma membrane during apoptosis.
      
 0.835
FASN3
Fatty acid synthase 3; Oxidoreductase activity; phosphopantetheine binding; fatty acid synthase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: biosynthetic process.
    
 0.808
FASN2
Fatty acid synthase 2 (FASN2) encodes an enzyme required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons.
    
 0.808
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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