STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9776Zinc finger matrin-type protein CG9776; It is involved in the biological process described with: positive regulation of transcription, DNA-templated; negative regulation of transcription, DNA-templated. (1260 aa)    
Predicted Functional Partners:
CG4119
BcDNA.LD23634; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome.
   
 
 0.794
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs [...]
    
 
 0.792
scaf6
SR-related CTD associated factor 6, isoform A; RNA binding. It is involved in the biological process described with: cellular calcium ion homeostasis; RNA processing.
   
 
 0.780
Cdc5
Cell division cycle 5, isoform A; DNA binding; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
 
 0.773
CG8565
ATP binding; protein serine/threonine kinase activity; MAP kinase activity. It is involved in the biological process described with: spliceosomal complex assembly; intracellular signal transduction; regulation of mRNA processing; regulation of gene expression; protein phosphorylation.
    
 
 0.716
Srpk79D
Serine-arginine protein kinase at 79D (Srpk79D) is required to prevent the formation of axonal protein aggregates containing the active zone-protein encoded by brp.
    
 
 0.716
SRPK
SR Protein Kinase (SRPK) encodes a protein involved in spindle microtubule assembly and karyosome formation in oocytes.
    
 
 0.716
su(f)
Suppressor of forked (su(f)) is an essential gene that encodes a protein involved in mRNA 3'-end processing (the nuclear cleavage/polyadenylation reaction) and alternative poly(A) site utilization. su(f) product accumulates in dividing cells where it is required for mitosis progression.
   
 
 0.712
Sf3b1
Splicing factor 3b subunit 1, isoform A; RNA binding; mRNA binding. It is involved in the biological process described with: spliceosomal complex assembly; mRNA splicing, via spliceosome.
   
 
 0.705
SC35
SR family splicing factor SC35 (SC35) encodes a mRNA binding protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site.
   
 
 0.656
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.