node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alg3 | CG3792 | FBpp0072004 | FBpp0078636 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | 0.689 |
Alg3 | Dpm1 | FBpp0072004 | FBpp0080817 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Probable dolichol-phosphate mannosyltransferase; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; Belongs to the glycosyltransferase 2 family. | 0.991 |
Alg3 | Mgat2 | FBpp0072004 | FBpp0084967 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2) encodes an enzyme involved in protein N-linked glycosylation. | 0.689 |
Alg3 | O-fut2 | FBpp0072004 | FBpp0070283 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of a number of protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. | 0.561 |
Alg3 | Pgant35A | FBpp0072004 | FBpp0080202 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Polypeptide N-acetylgalactosaminyltransferase 35A; Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2. Not involved in glycosylation of erythropoietin (EPO). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Protein modification by t [...] | 0.499 |
Alg3 | Pgant5 | FBpp0072004 | FBpp0078663 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate. In the larval midgut, required for O- glycosylation of apical and luminal proteins within copper cell [...] | 0.499 |
Alg3 | Pgant7 | FBpp0072004 | FBpp0311917 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...] | 0.450 |
Alg3 | Pmi | FBpp0072004 | FBpp0289218 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Transmembrane protein 11 homolog, mitochondrial; Pmi (Pmi) encodes a ubiquitous protein of the mitochondrial inner membrane that negatively controls the biogenesis of cristae membrane. Pmi-dependent cristae alterations are associated with impaired oxidative metabolism, abnormal mitochondrial shape/size, defective mitochondrial transport in neurons, and lead to stress-induced paralysis in adult flies. | 0.661 |
Alg3 | gny | FBpp0072004 | FBpp0079595 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. Involved in cuticle differentiation. | 0.991 |
Alg3 | nac | FBpp0072004 | FBpp0081352 | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling; Belongs to the TPT transporter family. SLC35C subfamily. | 0.488 |
CG3792 | Alg3 | FBpp0078636 | FBpp0072004 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. | 0.689 |
CG3792 | Dpm1 | FBpp0078636 | FBpp0080817 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Probable dolichol-phosphate mannosyltransferase; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; Belongs to the glycosyltransferase 2 family. | 0.876 |
CG3792 | Mgat2 | FBpp0078636 | FBpp0084967 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2) encodes an enzyme involved in protein N-linked glycosylation. | 0.679 |
CG3792 | O-fut2 | FBpp0078636 | FBpp0070283 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of a number of protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. | 0.790 |
CG3792 | Pgant35A | FBpp0078636 | FBpp0080202 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Polypeptide N-acetylgalactosaminyltransferase 35A; Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2. Not involved in glycosylation of erythropoietin (EPO). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Protein modification by t [...] | 0.790 |
CG3792 | Pgant5 | FBpp0078636 | FBpp0078663 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate. In the larval midgut, required for O- glycosylation of apical and luminal proteins within copper cell [...] | 0.698 |
CG3792 | Pgant7 | FBpp0078636 | FBpp0311917 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...] | 0.671 |
CG3792 | Pmi | FBpp0078636 | FBpp0289218 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Transmembrane protein 11 homolog, mitochondrial; Pmi (Pmi) encodes a ubiquitous protein of the mitochondrial inner membrane that negatively controls the biogenesis of cristae membrane. Pmi-dependent cristae alterations are associated with impaired oxidative metabolism, abnormal mitochondrial shape/size, defective mitochondrial transport in neurons, and lead to stress-induced paralysis in adult flies. | 0.839 |
CG3792 | gny | FBpp0078636 | FBpp0079595 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. Involved in cuticle differentiation. | 0.760 |
CG3792 | nac | FBpp0078636 | FBpp0081352 | Mannose-P-dolichol utilization defect 1 protein homolog; It is involved in the biological process described with: protein glycosylation; oligosaccharide biosynthetic process. | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling; Belongs to the TPT transporter family. SLC35C subfamily. | 0.719 |