STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp4ac1Probable cytochrome P450 4ac1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (509 aa)    
Predicted Functional Partners:
Cpr
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals. In the N-terminal section; belongs to the flavodoxin family.
 
 
 
 0.767
Ugt303B3
UDP-glycosyltransferase family 303 member B3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
   
 
 0.556
CG32984
Uncharacterized protein; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.
      
 0.549
Oatp33Eb
Organic anion transporting polypeptide 33Eb; Sodium-independent organic anion transmembrane transporter activity; transmembrane transporter activity; active transmembrane transporter activity. It is involved in the biological process described with: organic substance transport; sodium-independent organic anion transport; transmembrane transport.
   
  
 0.497
Oatp58Da
Solute carrier organic anion transporter family member; Sodium-independent organic anion transmembrane transporter activity; transmembrane transporter activity; active transmembrane transporter activity. It is involved in the biological process described with: organic substance transport; sodium-independent organic anion transport; transmembrane transport.
   
  
 0.495
CG33296
Uncharacterized protein, isoform B; Neurotransmitter:sodium symporter activity. It is involved in the biological process described with: neurotransmitter transport.
      
 0.491
Cyp12a4
Probable cytochrome P450 12a4, mitochondrial; Has a role in resistance to insecticide lufenuron, but no other insecticides.
  
 
0.475
Ugt37A2
UDP-glycosyltransferase family 37 member A2; UDP-glycosyltransferase activity; transferase activity, transferring hexosyl groups.
   
 
 0.474
CG13793
Uncharacterized protein; Neurotransmitter:sodium symporter activity; neurotransmitter transmembrane transporter activity. It is involved in the biological process described with: neurotransmitter transport.
   
  
 0.473
SmydA-9
SET and MYND domain containing, arthropod-specific, member 9, isoform A; Protein-lysine N-methyltransferase activity; histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression.
   
  
 0.462
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.