STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H15H15 (H15) encodes a T-box transcription factor that regulates the specification of cell fate in the heart and central nervous system. (660 aa)    
Predicted Functional Partners:
CG41561
Uncharacterized protein.
      
 0.837
Mst77Y-4
Male-specific transcript 77Y 4; It is involved in the biological process described with: spermatogenesis, exchange of chromosomal proteins.
      
 0.669
CG45765
MIP34412p1.
      
 0.669
Mst77Y-7
Male-specific transcript 77Y 7; It is involved in the biological process described with: spermatogenesis, exchange of chromosomal proteins.
      
 0.669
Mst77Y-9
Male-specific transcript 77Y 9; It is involved in the biological process described with: spermatogenesis, exchange of chromosomal proteins.
      
 0.669
Mst77Y-13
Male-specific transcript 77Y 13; It is involved in the biological process described with: spermatogenesis, exchange of chromosomal proteins.
      
 0.669
FDY
Flagrante delicto Y (FDY) is a gene inserted in the Y chromosome originated from a duplication of vig2.
      
 0.669
CG45764
Mst77Y-1.
      
 0.667
vig2
Vig2, isoform B; Vig2 (vig2) encodes a protein involved in heterochromatin organization, histone H3-K9 methylation and chromatin silencing regulation.
      
 0.609
Set1
Histone-lysine N-methyltransferase SETD1; Catalytic component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and is the main di- and trimethyltransferase throughout development. Set1-dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription.
    
   0.544
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.