STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CprNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals. In the N-terminal section; belongs to the flavodoxin family. (679 aa)    
Predicted Functional Partners:
Cyp6a2
Cytochrome P450 6a2; Is involved in the breakdown of synthetic insecticides and may be involved in the metabolism of insect hormones.
 
 
 
 0.952
Cyp6a8
Cytochrome P450 6a8; Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
 
 
 0.915
Cyp4d14
Probable cytochrome P450 4d14; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
 
 
 0.914
Cyp9f2
Probable cytochrome P450 9f2; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides; Belongs to the cytochrome P450 family.
 
 
 
 0.913
Cyp4d2
Cytochrome P450 4d2; Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
  
 
 0.913
Cyp4s3
Probable cytochrome P450 4s3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
  
 
 0.909
Cyp4c3
Cytochrome P450 4c3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
  
 
 0.909
Cyp6a18
Probable cytochrome P450 6a18; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
  
 
 0.906
Cyp4d20
Probable cytochrome P450 4d20; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
 
  
 
 0.862
Papss
PAPS synthetase (Papss) encodes an enzyme that catalyzes the synthesis of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), the sulfate donor compound in all sulfotransferase reactions. Maternally provided Papss product is required for the formation of the embryonic dorsal-ventral axis mediated by the sulfotransferase encoded by pip.
  
  
 0.855
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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