STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oatp26FSolute carrier organic anion transporter family member; Transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; active transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; sodium-independent organic anion transport; organic substance transport. (692 aa)    
Predicted Functional Partners:
Trm7-32
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 1; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
   
  
 0.701
CG7271
RE03769p; Nucleic acid binding.
      
 0.669
CG31997
RE42475p.
      
 0.669
glec
Gliolectin (glec) encodes a member of carbohydrate-binding proteins. glec product regulates glia-glia and glia-neuron interactions during neurogenesis and positively regulates Notch pathway during the specification of vein and intervein regions in wing imaginal discs.
      
 0.660
P5cr-2
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; L-proline biosynthetic process.
      
 0.627
Lmx1a
LIM homeobox transcription factor 1 alpha, isoform B; RNA polymerase II regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: neuron differentiation; positive regulation of transcription by RNA polymerase II.
   
   0.574
CG11638
RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization.
   
 
 0.543
rau
Rau, isoform A; Rau (rau) encodes a protein that sustains RTK signaling downstream of the product of htl or Egfr. This effect is mediated by the two Ras association (RA) domains that together show a binding preference for GTP-loaded Ras. rau depletion produces a rough eye phenotype and reduced differentiation of retinal wrapping glia.
      
 0.533
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
      
 0.528
Tsf1
Transferrin 1 (Tsf1) encodes an iron binding protein induced during the immune response. Iron sequestration is a classical host defense mechanism to combat bacterial infection.
   
  
 0.494
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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