STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gr28aPutative gustatory receptor 28a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression suggests also nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands. (450 aa)    
Predicted Functional Partners:
Gr58c
Putative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.
   
  
 0.877
Gr36c
Putative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.877
Gr59c
Putative gustatory receptor 59c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
 
 0.847
Gr59d
Putative gustatory receptor 59d; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
  
 0.819
Gr59a
Gustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
      
 0.795
Gr39a
Gustatory and pheromone receptor 39a, isoform C; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone.
   
  
 0.790
Gr32a
Gustatory and pheromone receptor 32a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Required for the response to N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide. Functions as a pheromone receptor for a male inhibitory pheromone and promotes male-male aggression and suppresses male-male courtship. Also promotes preferentially virgin females courting over mated females. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
   
  
 0.726
Gr93d
Gustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
   
  
 0.723
Gr43a
Gustatory receptor for sugar taste 43a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote feeding in hungry flies but suppress feeding in satiated flies.
   
  
 0.715
Nach
Sodium channel protein Nach; Nach (Nach) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family of proteins. It is mainly expressed in the tracheal system and functions in liquid clearance during tracheal development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
    0.709
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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