node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aprt | CG11811 | FBpp0312099 | FBpp0075994 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | 0.967 |
Aprt | CG5276 | FBpp0312099 | FBpp0081866 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | 0.911 |
Aprt | CG8891 | FBpp0312099 | FBpp0078684 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.944 |
Aprt | NTPase | FBpp0312099 | FBpp0304733 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | NTPase, isoform F; Uridine-diphosphatase activity; guanosine-diphosphatase activity; Belongs to the GDA1/CD39 NTPase family. | 0.908 |
Aprt | PrBP | FBpp0312099 | FBpp0079352 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; 3',5'-cyclic-nucleotide phosphodiesterase activity; protein binding. It is involved in the biological process described with: mushroom body development; sensory perception of light stimulus. | 0.903 |
Aprt | bur | FBpp0312099 | FBpp0310411 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Burgundy, isoform B; Burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. | 0.993 |
Arl2 | PrBP | FBpp0081328 | FBpp0079352 | ADP ribosylation factor-like 2 (Arl2) encodes a small GTPase within the ADP-ribosylation factor-like family. Arl2 product functions as a central regulator of microtubule growth and asymmetric division of neuroblasts. | Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; 3',5'-cyclic-nucleotide phosphodiesterase activity; protein binding. It is involved in the biological process described with: mushroom body development; sensory perception of light stimulus. | 0.959 |
Arl2 | Ras85D | FBpp0081328 | FBpp0081600 | ADP ribosylation factor-like 2 (Arl2) encodes a small GTPase within the ADP-ribosylation factor-like family. Arl2 product functions as a central regulator of microtubule growth and asymmetric division of neuroblasts. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.542 |
Arl2 | unc-119 | FBpp0081328 | FBpp0312199 | ADP ribosylation factor-like 2 (Arl2) encodes a small GTPase within the ADP-ribosylation factor-like family. Arl2 product functions as a central regulator of microtubule growth and asymmetric division of neuroblasts. | Protein unc-119 homolog; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. | 0.964 |
CG11811 | Aprt | FBpp0075994 | FBpp0312099 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.967 |
CG11811 | CG5276 | FBpp0075994 | FBpp0081866 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | 0.900 |
CG11811 | CG8891 | FBpp0075994 | FBpp0078684 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.954 |
CG11811 | NTPase | FBpp0075994 | FBpp0304733 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | NTPase, isoform F; Uridine-diphosphatase activity; guanosine-diphosphatase activity; Belongs to the GDA1/CD39 NTPase family. | 0.900 |
CG11811 | PrBP | FBpp0075994 | FBpp0079352 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; 3',5'-cyclic-nucleotide phosphodiesterase activity; protein binding. It is involved in the biological process described with: mushroom body development; sensory perception of light stimulus. | 0.905 |
CG11811 | bur | FBpp0075994 | FBpp0310411 | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | Burgundy, isoform B; Burgundy (bur) encodes a GMP synthetase required for axon guidance. It regulates the activity of the ubiquitin protease encoded by Usp7. | 0.958 |
CG5276 | Aprt | FBpp0081866 | FBpp0312099 | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.911 |
CG5276 | CG11811 | FBpp0081866 | FBpp0075994 | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | GH06691p; Guanylate kinase activity. It is involved in the biological process described with: purine nucleotide metabolic process. | 0.900 |
CG5276 | CG8891 | FBpp0081866 | FBpp0078684 | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.904 |
CG5276 | NTPase | FBpp0081866 | FBpp0304733 | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | NTPase, isoform F; Uridine-diphosphatase activity; guanosine-diphosphatase activity; Belongs to the GDA1/CD39 NTPase family. | 0.905 |
CG5276 | PrBP | FBpp0081866 | FBpp0079352 | CG5276 protein; Nucleoside-diphosphatase activity; guanosine-diphosphatase activity; calcium ion binding; nucleoside-triphosphatase activity; uridine-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. | Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; 3',5'-cyclic-nucleotide phosphodiesterase activity; protein binding. It is involved in the biological process described with: mushroom body development; sensory perception of light stimulus. | 0.900 |