STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rcd-1rRcd-1 related; It is involved in the biological process described with: negative regulation of translation; spermatogenesis; mRNA catabolic process; reproductive process. (290 aa)    
Predicted Functional Partners:
Pop2
Pop2, isoform E; Pop2 (Pop2) encodes a poly(A)-specific ribonuclease involved in translation inhibition.
   
 0.932
Cnot4
CCR4-NOT transcription complex subunit 4 (Cnot4) encodes a positive regulator of the Jak/Stat pathway which acts by stabilizing the DNA binding of the product of Stat92E.
    
 0.931
Not3
CCR4-NOT transcription complex subunit 3 (Not3) encodes a poly(A)-specific ribonuclease involved in translation inhibition.
    
 0.925
Not1
Not1, isoform H; Not1 (Not1) encodes a poly(A)-specific ribonuclease involved in translation inhibition and ovarian follicle cell development.
    
 0.925
CG13102
GEO12560p1.
      
 0.914
Rcd-1
Required for cell differentiation 1, isoform A; It is involved in the biological process described with: negative regulation of translation; mRNA catabolic process.
  
  
0.903
CG15262
FI22161p1; poly(A)-specific ribonuclease activity. It is involved in the biological process described with: negative regulation of translation; regulation of transcription, DNA-templated; nuclear-transcribed mRNA poly(A) tail shortening; regulation of stem cell population maintenance.
   
 0.857
CG9568
LP01634p.
      
 0.839
CG12237
LP01149p; Pyrophosphatase activity; phosphatase activity.
      
 0.836
gskt
Putative glycogen synthase kinase-3 homolog; Gasket (gskt) is a retro-transposed glycogen synthase kinase 3 gene, derived from sgg, that is required for male fertility. Like many genes retroposed from the X chromosome, it is highly expressed in the testis.
      
 0.835
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.