STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scatVacuolar protein sorting-associated protein 54; May be involved in retrograde transport from early and late endosomes to late Golgi (By similarity). Required during spermatogenesis for sperm individualization; Belongs to the VPS54 family. (940 aa)    
Predicted Functional Partners:
Vps52
Vacuolar protein sorting 52; Rab GTPase binding; syntaxin binding. It is involved in the biological process described with: retrograde transport, endosome to Golgi; lysosomal transport; Golgi to vacuole transport; endocytic recycling.
    
 0.999
Vps53
Vacuolar protein sorting 53; It is involved in the biological process described with: retrograde transport, endosome to Golgi; endocytic recycling.
   
 0.997
Vps50
Vacuolar protein sorting 50; It is involved in the biological process described with: endocytic recycling; retrograde transport, endosome to Golgi.
   
 0.993
Vps51
Vacuolar protein sorting-associated protein 51 homolog; May act as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans- Golgi network (TGN); Belongs to the VPS51 family.
   
 0.984
CG10646
RH33377p; It is involved in the biological process described with: protein ubiquitination.
    
 
 0.885
Syx16
Syntaxin 16 (Syx16) encodes a member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family. It is localized to late Golgi compartments and is part of a trans-SNARE complex responsible for endosome-to-Golgi/trans Golgi network retrograde transport.
   
 0.858
Syx6
Syntaxin 6, isoform E; SNARE binding; SNAP receptor activity.
   
 0.838
Cog3
Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.
   
 
 0.836
Cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.
   
 0.827
Cog7
Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.
   
 
 0.825
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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