Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG5096RE59088p. (491 aa)    
Predicted Functional Partners:
Tsp42Ec
Tetraspanin.
   
  
 0.842
CG33127
IP10114p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
 
 0.825
CG4301
ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 
 0.816
CG3987
GH09123p; It is involved in the biological process described with: mesoderm development.
   
    0.802
Tsp29Fa
Tetraspanin.
   
    0.787
Lapsyn
Leucine-rich repeat activity-regulated protein at synapses (Lapsyn) encodes a member of the leucine-rich repeat (LRR) family of cell surface protein. It is expressed in glial cells and required for branch morphogenesis of astrocyte-like glia in the visual system and other areas of the central nervous system during larval and pupal development.
  
  
 0.766
Decay
Death executioner caspase related to Apopain/Yama (Decay) encodes one of the seven members of the caspase family of cysteine proteases. It has substrate specificity similar to the effector caspases encoded by Drice and Dcp-1; Belongs to the peptidase C14A family.
   
  
 0.695
CG9380
MIP09469p.
   
    0.692
Mocs1
Cyclic pyranopterin monophosphate synthase; Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). Mocs1a catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and Mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family.
   
  
 0.655
ver
Verrocchio, isoform A; Verrocchio (ver) encodes a member of the terminin complex, which prevents telomere fusions. It is required for telomere maintenance.
      
 0.654
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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