Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CG31871RE24765p. (531 aa)    
Predicted Functional Partners:
colt
Congested-like trachea protein; Putative mitochondrial carrier of unknown solute specificity. Required for gas-filling of the tracheal system at hatching time of the embryo and for normal epithelial morphogenesis of the wings.
      
 0.654
Lip1
Lipase 1; Could be a digestive enzyme; Belongs to the AB hydrolase superfamily. Lipase family.
  
 
 
0.627
CG3511
LD39850p; Peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization.
      
 0.592
Hsc70-1
Heat shock 70 kDa protein cognate 1.
  
  
 0.587
dbf
AT30637p; Nucleic acid binding; zinc ion binding.
   
    0.514
sktl
Skittles, isoform A; Skittles (sktl) encodes the major Phosphatidylinositol 4-Phosphate-5 kinase (PI4P5K), catalysing the formation of phosphoinositol-4,5-bisphosphate (PIP4,5). The sktl product is involved in many cellular processes involving (PIP4,5), such as endocytosis. It plays an important role in cell polarity by controlling the localization of the product encoded by baz.
      
 0.474
Lip2
Lipase; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; Belongs to the AB hydrolase superfamily. Lipase family.
  
  
 
0.462
CG11598
Lipase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: multicellular organism reproduction; lipid metabolic process.
  
 
 
0.455
CG8093
Lipase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: multicellular organism reproduction; lipid metabolic process.
  
 
 
0.455
CG11608
Lipase; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; multicellular organism reproduction; Belongs to the AB hydrolase superfamily. Lipase family.
  
 
 
0.453
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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