| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG4751 | Prosalpha5 | FBpp0079789 | FBpp0086066 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 0.967 |
| CG4751 | Prosalpha7 | FBpp0079789 | FBpp0089041 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | Proteasome subunit alpha type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family. | 0.968 |
| CG4751 | Prosbeta7 | FBpp0079789 | FBpp0078448 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | Proteasome subunit beta type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family. | 0.962 |
| CG4751 | Rpn1 | FBpp0079789 | FBpp0074662 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.952 |
| CG4751 | Rpn2 | FBpp0079789 | FBpp0303405 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome non-ATPase regulatory subunit 1; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. | 0.973 |
| CG4751 | Rpn6 | FBpp0079789 | FBpp0086603 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly (By similarity). May act as linker between 19S regulatory subunit and the 20S proteasome core. | 0.956 |
| CG4751 | Rpn7 | FBpp0079789 | FBpp0083687 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome non-ATPase regulatory subunit 6; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. | 0.950 |
| CG4751 | Rpt1 | FBpp0079789 | FBpp0088021 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome regulatory complex subunit p48B; Regulatory particle triple-A ATPase 1 (Rpt1) encodes an AAA-type ATPase protein that forms part of the heterohexameric ATPase ring of the regulatory complex of the 26S proteasome. | 0.965 |
| CG4751 | Rpt2 | FBpp0079789 | FBpp0311982 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 26S proteasome regulatory subunit 4; Regulatory particle triple-A ATPase 2 (Rpt2) encodes one of six ATPases that form the base of the regulatory 19S cap of the proteasome. The Rpt2 product is involved in the recognition of specific substrates destined for degradation, such as those involved in Notch signalling pathway. | 0.958 |
| CG4751 | Rpt5 | FBpp0079789 | FBpp0083843 | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | Regulatory particle triple-A ATPase 5 (Rpt5) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. | 0.952 |
| Prosalpha5 | CG4751 | FBpp0086066 | FBpp0079789 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | MPN domain-containing protein CG4751; Probable protease; Belongs to the peptidase M67 family. | 0.967 |
| Prosalpha5 | Prosalpha7 | FBpp0086066 | FBpp0089041 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | Proteasome subunit alpha type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family. | 0.999 |
| Prosalpha5 | Prosbeta7 | FBpp0086066 | FBpp0078448 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | Proteasome subunit beta type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family. | 0.999 |
| Prosalpha5 | Rpn1 | FBpp0086066 | FBpp0074662 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
| Prosalpha5 | Rpn2 | FBpp0086066 | FBpp0303405 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome non-ATPase regulatory subunit 1; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. | 0.997 |
| Prosalpha5 | Rpn6 | FBpp0086066 | FBpp0086603 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly (By similarity). May act as linker between 19S regulatory subunit and the 20S proteasome core. | 0.999 |
| Prosalpha5 | Rpn7 | FBpp0086066 | FBpp0083687 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome non-ATPase regulatory subunit 6; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. | 0.999 |
| Prosalpha5 | Rpt1 | FBpp0086066 | FBpp0088021 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome regulatory complex subunit p48B; Regulatory particle triple-A ATPase 1 (Rpt1) encodes an AAA-type ATPase protein that forms part of the heterohexameric ATPase ring of the regulatory complex of the 26S proteasome. | 0.999 |
| Prosalpha5 | Rpt2 | FBpp0086066 | FBpp0311982 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | 26S proteasome regulatory subunit 4; Regulatory particle triple-A ATPase 2 (Rpt2) encodes one of six ATPases that form the base of the regulatory 19S cap of the proteasome. The Rpt2 product is involved in the recognition of specific substrates destined for degradation, such as those involved in Notch signalling pathway. | 0.999 |
| Prosalpha5 | Rpt5 | FBpp0086066 | FBpp0083843 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. | Regulatory particle triple-A ATPase 5 (Rpt5) encodes a component of the 26S proteasome, which degrades polyubiquitinated proteins in the cytoplasm and nucleus. | 0.999 |