STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG14921AT10515p; It is involved in the biological process described with: cilium movement; inner dynein arm assembly; outer dynein arm assembly; sensory perception of sound. (240 aa)    
Predicted Functional Partners:
Nop17l
Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. Belongs to the PIH1 family. Kintoun subfamily.
    
 
 0.914
CG17083
AT03545p.
   
 
 0.862
CG5048
AT12351p; Chaperone binding. It is involved in the biological process described with: flagellated sperm motility.
   
 
 0.845
CG18675
Cilia- and flagella-associated protein 298; It is involved in the biological process described with: regulation of cilium movement; Belongs to the CFAP298 family.
   
  
 0.840
Wdr92
WD repeat domain 92; Protein domain specific binding; ubiquitin binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; calcineurin-NFAT signaling cascade.
   
 
 0.698
HEATR2
Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.
   
  
 0.670
CG17669
Dynein assembly factor 3, axonemal homolog; Required for the assembly of axonemal inner and outer dynein arms; Belongs to the DNAAF3 family.
   
  
 0.520
Pih1D1
PIH1 domain containing 1, isoform D.
    
 
 0.476
Rsph1
AT19426p; It is involved in the biological process described with: axoneme assembly.
   
 
 0.452
Uxt
Uxt prefoldin-like subunit (Uxt) encodes a protein that suppresses growth of larval neuromuscular junctions via an unknown mechanism.
    
 
 0.442
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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