Protein hunchback; Gap class segmentation protein that controls development of head structures; Belongs to the hunchback C2H2-type zinc-finger protein family.

Segmentation protein even-skipped; May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair- rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes; Belongs to the even-skipped homeobox family.

POU domain protein 2, isoform B; DNA-binding regulatory protein implicated in early development. Involved in neuronal cell fate decision. May act as an octamer-dependent activator of transcription. Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system.

Zn finger homeodomain 2 (zfh2) encodes a putative transcription factor. Its roles include specification of cell fates and promotion of apoptosis during CNS development, and proximal-distal patterning during wing and leg imaginal disc development.

Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Extra-extra (exex) encodes a homeodomain transcription factor that is expressed in and regulates the differentiation of motor neurons that project axons to ventral body wall muscles. Within the central nervous system, the product of exex negatively interacts with the products of Lim3 and eve to govern neuronal specification and differentiation. The roles of the product of exex include neuronal specification and differentiation.

Steroid receptor seven-up, isoform A; Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC- 2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs). Belongs to the nuclear hormone receptor family. NR2 subfamily.

GTX/Nkx6B-like homeodomain protein; HGTX (HGTX) encodes a homeodomain transcription factor that acts in parallel with the product of exex to promote the development and differentiation of motor neurons that innervate ventral body wall muscles. Its major roles include neuronal specification and differentiation.

Protein tyrosine phosphatase 69D (Ptp69D) encodes a transmembrane receptor tyrosine phosphatase (RPTP). It genetically interacts with the other RPTP genes and its mutants have embryonic motor axon guidance phenotypes. In particular, Ptp10D-Ptp69D double mutants have a strong phenotype in which embryonic CNS axons abnormally cross the ventral midline. The product of Ptp69D physically and genetically interacts with the product of Dscam1 to regulate arborization of mechanosensory neurons; Belongs to the protein-tyrosine phosphatase family. Receptor class subfamily.