Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Nepl7Neprilysin-like 7, isoform A; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis. (669 aa)    
Predicted Functional Partners:
Nepl11
Neprilysin-like 11; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.779
Nepl3
Neprilysin-like 3; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
   
  
 0.655
ACXE
Adenylyl cyclase X E; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.652
CG17572
RH69521p; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.651
RpL7-like
Ribosomal protein L7-like, isoform A; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation.
      
 0.651
Nepl9
Neprilysin-like 9; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
      
 0.498
Sidpn
Similar to deadpan; Protein dimerization activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of neurogenesis; anterior/posterior pattern specification; negative regulation of transcription by RNA polymerase II; cell differentiation; regulation of transcription, DNA-templated.
      
 0.478
CG15657
Uncharacterized protein, isoform A.
      
 0.475
Nepl21
Neprilysin-like 21; Metalloendopeptidase activity. It is involved in the biological process described with: proteolysis.
  
   
0.450
CG18600
LD14127p; DNA-directed 5'-3' RNA polymerase activity; DNA binding. It is involved in the biological process described with: transcription elongation from RNA polymerase I promoter; nucleolar large rRNA transcription by RNA polymerase I; RNA polymerase I preinitiation complex assembly.
   
  
 0.447
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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